Szopinski J, Pantanowitz D, Jaros G G
Department of Family Medicine, Coronation Hospital, Johannesburg.
S Afr Med J. 1998 Feb;88(2):146-50.
To estimate the diagnostic accuracy as well as the scope of utilisation of a new bio-electronic method of organ diagnostics.
Double-blind comparative study of the diagnostic results obtained by means of organ electrodermal diagnostics (OED) and clinical diagnoses, as a criterion standard.
Department of Surgery, Helen Joseph Hospital, Johannesburg.
70 pre-selected inpatients of mean age 36 (SD = 7) years with suspected pathology of one (or more) of the following organs: oesophagus, stomach, duodenum, biliary tract, pancreas, colon, kidneys and urinary tract. In total, 276 of the abovementioned internal organs were selected for statistical consideration.
The difference between the so-called basic electrical impedance of the skin and the impedance value established for a particular organ projection area (the skin zone corresponding to a particular internal organ).
In total 250 true OED results were obtained from the 276 subjects considered: detection rate 90.6% (95% CI 87.1-94.1%). Established OED sensitivity was 91.8% (95% CI 88.6-95.0%) and OED specificity equalled 89.9% (95% CI 86.4-93.4%). The predictive value for positive OED results was 83.3% (95% CI 78.9-87.7%) and for negative OED results 95.2% (95% CI 92.0-98.4%). The OED results were affected neither by the type nor the aetiology of disease, i.e. OED estimates the actual extent of the pathological process within particular organs but does not explain the cause of pathology directly. No side-effects of the OED examinations were observed.
So-called organ projection areas do exist on the skin surface. The electrical impedance of the projection areas corresponding to diseased organs is increased, relative to that of healthy organ-related skin zones. The difference in impedance is proportional to the intensity of the pathological process. OED, which utilises these electrical phenomena of the skin, may detect diseased organs and estimate the extent of pathological process activity within these organs.
评估一种新的生物电子器官诊断方法的诊断准确性及应用范围。
采用器官皮肤电诊断法(OED)与作为标准对照的临床诊断所获结果进行双盲对比研究。
约翰内斯堡海伦·约瑟夫医院外科。
70名预先选定的住院患者,平均年龄36(标准差 = 7)岁,怀疑有以下一个(或多个)器官病变:食管、胃、十二指肠、胆道、胰腺、结肠、肾脏及尿路。共计276个上述内脏器官纳入统计分析。
皮肤所谓的基础电阻抗与特定器官投影区域(对应特定内脏器官的皮肤区域)所确定的阻抗值之间的差异。
在纳入分析的276名受试者中,共获得250个真实的OED结果:检出率90.6%(95%可信区间87.1 - 94.1%)。既定的OED敏感性为91.8%(95%可信区间88.6 - 95.0%),OED特异性为89.9%(95%可信区间86.4 - 93.4%)。OED阳性结果的预测值为83.3%(95%可信区间78.9 - 87.7%),阴性结果的预测值为95.2%(95%可信区间92.0 - 98.4%)。OED结果不受疾病类型或病因影响,即OED可评估特定器官内病理过程的实际范围,但不能直接解释病理原因。未观察到OED检查的副作用。
皮肤表面确实存在所谓的器官投影区域。与患病器官对应的投影区域的电阻抗相对于健康器官相关皮肤区域的电阻抗增加。阻抗差异与病理过程的强度成正比。利用皮肤这些电现象的OED可检测患病器官并评估这些器官内病理过程活动的范围。