通过对不同年龄的大鼠反复给予三羟甲基氨基甲烷（THAM）来增强肾皮质切片中肾小管有机碱的蓄积。
Enhancement of tubular organic base accumulation in renal cortical slices by repeated administrations of Tris-hydroxymethyl aminomethane, tromethamol (THAM) to rats of different ages.
作者信息
Stopp M, Bräunlich H
出版信息
Experientia. 1976 Sep 15;32(9):1182-4. doi: 10.1007/BF01927615.
PMID:971756
Abstract
After repeated THAM administrations to rats of different ages, an enhancement of THAM accumulation in renal cortical slices was observed, except in newborns. This effect can be interpreted as a specific substrate stimulation of the organic base transport system.
摘要
对不同年龄的大鼠反复给予三羟甲基氨基甲烷（THAM）后，除新生大鼠外，观察到肾皮质切片中THAM蓄积增加。这种效应可解释为有机碱转运系统的特异性底物刺激。
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