Giladi M, Lembo A, Johnson B L
Div. of Infectious Diseases, UCLA School of Medicine, USA.
Infection. 1998 Jul-Aug;26(4):234-5. doi: 10.1007/BF02962370.
Cytomegalovirus (CMV) gastritis has been reported in transplant patients. Symptoms are considered nonspecific, and gastroscopy with biopsy is usually performed to establish the diagnosis. Three patients are described here 1 to 3 months after solid organ transplantation, with primary CMV gastritis, confirmed by gastroscopy, histopathologic examination and cultures. The clinical presentation in all three cases was sharp epigastric pain that decreased in a supine position, increased while sitting and further increased when standing or walking. The epigastric pain completely resolved after treatment with ganciclovir. To the best of our knowledge, such postural epigastric pain has not been described as a specific symptom in any other clinical entity and may be a unique sign of primary CMV gastritis.
移植患者中曾有巨细胞病毒（CMV）胃炎的报道。其症状被认为是非特异性的，通常需进行胃镜检查及活检以明确诊断。本文描述了3例实体器官移植术后1至3个月的患者，经胃镜检查、组织病理学检查及培养确诊为原发性CMV胃炎。所有3例患者的临床表现均为上腹部剧痛，仰卧位时疼痛减轻，坐位时加重，站立或行走时进一步加重。经更昔洛韦治疗后，上腹部疼痛完全缓解。据我们所知，这种体位性上腹部疼痛在其他任何临床病症中均未被描述为特异性症状，可能是原发性CMV胃炎的独特体征。
