Kouyanou Kyriaki, Pither Charles E, Rabe-Hesketh Sophia, Wessely Simon
King's College School of Medicine and Dentistry and the Institute of Psychiatry, 103 Denmark Hill, London SE5 8AZ, UK INPUT Pain Management Unit, St. Thomas' Hospital, London, UK.
Pain. 1998 Jun;76(3):417-426. doi: 10.1016/S0304-3959(98)00074-8.
We report a case control study comparing patients attending a pain clinic whose symptoms were not considered medically explained (cases) with those whose symptoms were considered medically explained (controls). Principal comparisons were psychiatric morbidity, medication use, and iatrogenic factors assessed by interview, and questionnaire measures of anxiety, depression, functional impairment, coping strategies and pain beliefs. Medically unexplained symptoms were associated with the presence of psychiatric morbidity (odds ratio = 3.4, 95% C.I.: 1.4,8.2), and of possible iatrogenic factors. There were no significant differences with regards to medication abuse/dependence.
我们报告了一项病例对照研究，该研究比较了前往疼痛诊所就诊的患者，其中症状未被认为有医学解释的患者（病例组）与症状被认为有医学解释的患者（对照组）。主要比较内容包括通过访谈评估的精神疾病发病率、药物使用情况和医源性因素，以及焦虑、抑郁、功能障碍、应对策略和疼痛信念的问卷调查指标。无法用医学解释的症状与精神疾病发病率（优势比 = 3.4，95%置信区间：1.4, 8.2）以及可能的医源性因素有关。在药物滥用/依赖方面没有显著差异。
