Department of Psychiatry & Behavioral Sciences, University of Washington, Seattle, WA.
University of Washington Twin Registry, University of Washington, Seattle, WA.
J Psychosom Res. 2015 Jan;78(1):58-63. doi: 10.1016/j.jpsychores.2014.09.019. Epub 2014 Oct 2.
Pain is a complex phenomenon influenced by context and person-specific factors. Affective dimensions of pain involve both enduring personality traits and fleeting emotional states. We examined how personality traits and emotional states are linked with clinical and evoked pain in a twin sample.
99 female twin pairs were evaluated for clinical and evoked pain using the McGill Pain Questionnaire (MPQ) and dolorimetry, and completed the 120-item International Personality Item Pool (IPIP), the Positive and Negative Affect Scale (PANAS), and ratings of stress and mood. Using a co-twin control design we examined a) the relationship of personality traits and emotional states with clinical and evoked pain and b) whether genetics and common environment (i.e. familial factors) may account for the associations.
Neuroticism was associated with the sensory component of the MPQ; this relationship was not confounded by familial factors. None of the emotional state measures was associated with the MPQ. PANAS negative affect was associated with lower evoked pressure pain threshold and tolerance; these associations were confounded by familial factors. There were no associations between IPIP traits and evoked pain.
A relationship exists between neuroticism and clinical pain that is not confounded by familial factors. There is no similar relationship between negative emotional states and clinical pain. In contrast, the relationship between negative emotional states and evoked pain is strong while the relationship with enduring personality traits is weak. The relationship between negative emotional states and evoked pain appears to be non-causal and due to familial factors.
疼痛是一种受环境和个体因素影响的复杂现象。疼痛的情感维度既包括持久的人格特质，也包括短暂的情绪状态。我们在双胞胎样本中研究了人格特质和情绪状态如何与临床疼痛和诱发疼痛相关联。
99 对女性双胞胎使用 McGill 疼痛问卷（MPQ）和痛觉计评估临床疼痛和诱发疼痛，并完成了 120 项国际人格项目池（IPIP）、正负情绪量表（PANAS）以及压力和情绪评定。我们使用同卵双胞胎对照设计，考察了 a）人格特质和情绪状态与临床疼痛和诱发疼痛的关系，以及 b）遗传和共同环境（即家庭因素）是否可以解释这些关联。
神经质与 MPQ 的感觉成分相关；这种关系不受家庭因素的影响。情绪状态测量中的任何一种都与 MPQ 无关。PANAS 负性情绪与较低的诱发压力疼痛阈值和耐受力相关；这些关联受家庭因素影响。IPIP 特质与诱发疼痛之间没有关联。
神经质与临床疼痛之间存在关系，不受家庭因素影响。情绪状态与临床疼痛之间没有类似的关系。相反，情绪状态与诱发疼痛之间的关系较强，而与持久的人格特质之间的关系较弱。情绪状态与诱发疼痛之间的关系似乎是非因果的，并且与家庭因素有关。
