Nacro B, Bonkoungou P, Nagalo K, Tall F R, Curtis V
Service de Pédiatrie, Centre Muraz, Bobo Dioulasso, Burkina Faso.
Med Trop (Mars). 1998;58(1):47-50.
Data concerning Cryptosporidium parvum infection in Black Africa are highly fragmentary. A 12-month study was carried out on 1392 stool specimens from children under 36 months of age with (n = 756) or without diarrhea (n = 629) in the Pediatric Department of Bobo Dioulasso Hospital in Burkina Faso. In 558 children HIV blood tests were also performed. The phenicated fuchsin technique was used to identify Cryptosporidia oocysts. Results were positive in 72 of the 1392 stool specimens tested (5.2%) and in 59 of the 756 stool samples from children with diarrhea (7.8%). Oocysts were not detected in any child under the age of 6 months and the highest incidence of infection was between 6 and 23 months. Detection of oocysts during this year long study was significantly higher from April to June, which corresponds to the beginning of the rainy season in Burkina Faso. Occurrence of diarrhea was not significantly correlated with parasite density. Presence of oocysts was correlated with malnutrition (p < 0.01) and rotavirus infection (p < 0.05). Of the 558 children who underwent HIV testing, only one was positive. In contrast the incidence of HIV infections in the overall population tested was 7%. This study indicates that cryptosporidiasis is a major factor in development of diarrhea and dehydration in the pediatric hospital setting of Burkina Faso. Two other notable findings are that occurrence of cryptosporidiosis is closely linked to hygiene in the population but is not significantly correlated with HIV infection in the pediatric setting in Africa.
关于非洲黑人地区微小隐孢子虫感染的数据非常零散。在布基纳法索博博迪乌拉索医院儿科,对1392份36个月以下儿童的粪便标本进行了为期12个月的研究,其中腹泻儿童(n = 756)和无腹泻儿童(n = 629)的标本各有一部分。还对558名儿童进行了HIV血液检测。采用酚品红染色技术鉴定隐孢子虫卵囊。在检测的1392份粪便标本中,72份结果呈阳性(5.2%),腹泻儿童的756份粪便样本中有59份呈阳性(7.8%)。6个月以下儿童未检测到卵囊,感染发生率最高的年龄段为6至23个月。在这一年的研究中,4月至6月卵囊检测率显著更高,这与布基纳法索雨季开始时间相符。腹泻的发生与寄生虫密度无显著相关性。卵囊的存在与营养不良(p < 0.01)和轮状病毒感染(p < 0.05)相关。在接受HIV检测的558名儿童中,只有1名呈阳性。相比之下,总体检测人群中HIV感染率为7%。这项研究表明,隐孢子虫病是布基纳法索儿科医院腹泻和脱水发生的主要因素。另外两个值得注意的发现是,隐孢子虫病的发生与人群卫生密切相关,但在非洲儿科环境中与HIV感染无显著相关性。