Chauhan A J, Krishna M T, Frew A J, Holgate S T
Southampton University Hospitals NHS Trust, UK.
Rev Environ Health. 1998 Jan-Jun;13(1-2):73-90.
Epidemiological evidence suggests that exposure to nitrogen dioxide (NO2) through the use of unvented gas cookers in homes is associated with respiratory symptoms. Toxicological evidence, mainly in animal models, suggests that NO2 may increase the susceptibility to infection by viruses and bacteria. This review examines the evidence and proposes mechanisms whereby such exposure may occur, in particular how NO2 may aggravate respiratory symptoms in the presence of coexistent infection.
流行病学证据表明，在家中使用无通风口的燃气灶具接触二氧化氮（NO₂）与呼吸道症状有关。毒理学证据（主要来自动物模型）表明，NO₂可能会增加对病毒和细菌感染的易感性。本综述审视了相关证据，并提出了可能发生此类接触的机制，特别是在存在合并感染的情况下，NO₂可能如何加重呼吸道症状。
