Sugita T, Nishikawa A, Ikeda R, Shinoda T, Sakashita H, Sakai Y, Yoshizawa Y
Department of Microbiology, Meiji College of Pharmacy, Tanashi, Tokyo, Japan.
Microbiol Immunol. 1998;42(7):475-8. doi: 10.1111/j.1348-0421.1998.tb02312.x.
Trichosporon species have been known to cause summer-type hypersensitivity pneumonitis (SHP). During the isolation of yeasts from an SHP patient's house, we recovered a strain belonging to the genus Trichosporon. Morphologically, the isolate produced rectangular arthroconidia when grown on corn meal agar. DNA-DNA hybridization experiments identified the isolate as T. ovoides. A slide agglutination test using specific factor sera demonstrated that the serotype of the strain was type II. Previously, T. asahii, a serotype II species, was considered to be the major antigen of SHP, but it is possible that T. ovoides may also be responsible for SHP. This is the first report of T. ovoides isolated from an SHP patient's home environment.
已知毛孢子菌属会引起夏季型过敏性肺炎(SHP)。在从一名SHP患者家中分离酵母时,我们分离出了一株属于毛孢子菌属的菌株。从形态学上看,该分离株在玉米粉琼脂上生长时会产生长方形关节孢子。DNA-DNA杂交实验确定该分离株为卵形毛孢子菌。使用特异性因子血清进行的玻片凝集试验表明该菌株的血清型为II型。此前,血清型II的阿萨希毛孢子菌被认为是SHP的主要抗原,但卵形毛孢子菌也可能导致SHP。这是首次报道从SHP患者家庭环境中分离出卵形毛孢子菌。