日本以外地区的夏季型过敏性肺炎：一例病例报告及最新研究状况

Summer-type hypersensitivity pneumonitis outside Japan: a case report and the state of the art.

作者信息

Yoo C G, Kim Y W, Han S K, Nakagawa K, Suga M, Nishiura Y, Ando M, Shim Y S

机构信息

Department of Internal Medicine, Seoul National University, College of Medicine, Seoul National University Hospital, Korea.

出版信息

Respirology. 1997 Mar;2(1):75-7. doi: 10.1111/j.1440-1843.1997.tb00057.x.

DOI:10.1111/j.1440-1843.1997.tb00057.x

PMID:9424409

Abstract

A 61-year-old Korean housewife developed dyspnoea, cough and weight loss in the summer of 1994. The case was diagnosed as definite summer-type hypersensitivity pneumonitis (SHP) according to the criteria proposed for hypersensitivity pneumonitis and for SHP. Her serum antibodies to Trichosporon were positive. Her symptoms were exacerbated after she returned home and Trichosporon was isolated from the patient's home, indicating Trichosporon as the causative antigen. This is the first confirmed case of SHP outside Japan. On the basis of our research in SHP to date, we propose that SHP occurs in other Asian countries and that the assay of anti-Trichosporon antibodies is useful for the diagnosis of the disease.

摘要

一名61岁的韩国家庭主妇于1994年夏天出现呼吸困难、咳嗽和体重减轻症状。根据提出的过敏性肺炎和夏季型过敏性肺炎的标准，该病例被诊断为确诊的夏季型过敏性肺炎（SHP）。她的抗毛孢子菌血清抗体呈阳性。她回家后症状加重，且从患者家中分离出毛孢子菌，表明毛孢子菌是致病抗原。这是日本境外首例确诊的夏季型过敏性肺炎病例。基于我们目前对夏季型过敏性肺炎的研究，我们提出夏季型过敏性肺炎也发生在其他亚洲国家，并且抗毛孢子菌抗体检测对该疾病的诊断有用。