Toyoki Y, Satoh S, Morioka G, Asano M, Nomura K
Division of Surgery, Yonaizawa Municipal Hospital, Akita, Japan.
J Gastroenterol. 1998 Aug;33(4):575-7. doi: 10.1007/s005350050136.
We report a case of acquired hypertrichosis lanuginosa associated with rectal cancer and discuss the cutaneous symptoms as a marker of malignancy. A 75-year-old man had noticed increasing growth of hair over his entire body 4 months before he was admitted to our hospital because of bloody stools. Advanced rectal cancer was diagnosed, and he underwent sigmoidocolostomy. After the operation, levels of serum adrenocorticotrophic hormone and cortisone were normal, as were urinary levels of 17-ketosteroids and 17-hydroxycorticosteroids. Levels of carcinoembryonic antigen and carbohydrate antigen 19-9 were slightly elevated. The patient died 5 months after the operation because of peritonitis carcinomatosa. We suggest that hypertrichosis lanuginosa is a marker of internal malignant tumors.
我们报告一例与直肠癌相关的获得性毳毛增多症病例，并讨论皮肤症状作为恶性肿瘤标志物的情况。一名75岁男性在因便血入院前4个月注意到全身毛发增多。诊断为晚期直肠癌，他接受了乙状结肠造口术。术后，血清促肾上腺皮质激素和可的松水平正常，尿17-酮类固醇和17-羟皮质类固醇水平也正常。癌胚抗原和糖类抗原19-9水平略有升高。患者术后5个月因癌性腹膜炎死亡。我们认为毳毛增多症是体内恶性肿瘤的一个标志物。
