Janiri L, Hadjichristos A, Buonanno A, Rago R, Mannelli P, de Risio S
Drug Addiction Unit, Institute of Psychiatry, Faculty of Medicine, Catholic University, Rome, Italy.
Alcohol Alcohol. 1998 Jul-Aug;33(4):362-5. doi: 10.1093/oxfordjournals.alcalc.a008405.
Serotonergic drugs have been proven to be helpful to alcoholics in maintaining abstinence. In this open study, we report that the atypical antidepressant trazodone at low doses was able to significantly decrease craving for alcohol, depressive, and anxious symptoms in a number (25) of detoxified alcohol-dependent subjects after 3 months of treatment. Trazodone may, therefore, be an adjuvant in the therapy of alcoholism.
血清素能药物已被证明有助于酗酒者保持戒酒状态。在这项开放性研究中，我们报告称，低剂量的非典型抗抑郁药曲唑酮在治疗3个月后，能够显著降低25名已戒酒的酒精依赖者对酒精的渴望、抑郁和焦虑症状。因此，曲唑酮可能是治疗酒精中毒的一种辅助药物。
