Mbaria J M, Maitho T E, Mitema E S, Muchiri D J
University of Nairobi, Faculty of Veterinary Medicine, Department of Public Health, Pharmacology and Toxicology, Kenya.
Trop Anim Health Prod. 1998 Feb;30(1):17-22. doi: 10.1023/a:1005005208588.
The efficacies of pyrethrum marc and of albendazole against experimental sheep gastrointestinal nematode infection were compared. Sheep was infected orally with 10,000 larvae (Haemonchus spp. (60.1%), Oesophagostomum spp. (13.9%), Trichostrongylus spp. (13.2%), Cooperia spp. (8.3%), Nematodirus spp. (3.5%), Strongyloides spp. (0.8%) and Ostertagia spp. (0.2%). Faecal egg count reduction in albendazole-treated sheep was 100% by day 4 following treatment, compared to 37.03%, 31.3%, 38.9% and 51.8% on days 4, 6, 8 and 10 in pyrethrum mare-treated sheep. These reductions were statistically significant on days 8 and 10 post-treatment (p < 0.05). The potential for using pyrethrins for helminth treatment is discussed.
比较了除虫菊残渣和阿苯达唑对实验性绵羊胃肠道线虫感染的疗效。绵羊经口感染10000条幼虫（血矛线虫属（60.1%）、食道口线虫属（13.9%）、毛圆线虫属（13.2%）、古柏线虫属（8.3%）、细颈线虫属（3.5%）、类圆线虫属（0.8%）和奥斯特他线虫属（0.2%））。阿苯达唑治疗的绵羊在治疗后第4天粪便虫卵计数减少100%，而除虫菊残渣治疗的绵羊在第4、6、8和10天的减少率分别为37.03%、31.3%、38.9%和51.8%。这些减少率在治疗后第8天和第10天具有统计学意义（p<0.05）。讨论了使用除虫菊酯治疗蠕虫的可能性。
