Kocsis J H
Cornell Medical Center, New York Hospital, New York 10021, USA.
J Clin Psychiatry. 1998;59 Suppl 10:13-5.
This article reviews what is known about the epidemiology, clinical characteristics, and treatment of dysthymia in the geriatric age group. Although less common in the elderly than in young adults, dysthymia may have its onset in middle or late life. Geriatric dysthymia appears to have less associated psychiatric comorbidity and closer links to severe life stresses, particularly medical illnesses, than dysthymia with early-age onset. Preliminary reports of response to antidepressant medications are encouraging in the elderly, but randomized, placebo-controlled clinical trials are needed in samples of dysthymic patients in this age group.
本文综述了老年人群中恶劣心境障碍的流行病学、临床特征及治疗方面的已知情况。尽管恶劣心境障碍在老年人中不如在年轻人中常见,但它可能在中年或老年期起病。与早发性恶劣心境障碍相比,老年期恶劣心境障碍似乎较少伴有精神科共病,且与严重生活应激,尤其是躯体疾病联系更为紧密。抗抑郁药物治疗反应的初步报告对老年人来说是令人鼓舞的,但需要在该年龄组的恶劣心境障碍患者样本中进行随机、安慰剂对照的临床试验。