Anjum I, Ahmed M, Azzopardi A, Mufti G R
Department of Urology, Medway Hospital, Gillingham, Kent, England.
J Urol. 1998 Sep;160(3 Pt 1):792-3. doi: 10.1016/S0022-5347(01)62788-5.
We assess the role of acute prostatic infarction and prostatic inflammation in causing acute urinary retention in patients with benign prostatic hyperplasia (BPH).
A prospective controlled clinicopathological study was undertaken comparing 35 patients who presented with acute urinary retention secondary to BPH with another 35 patients with symptomatic BPH. All 70 patients were treated with transurethral resection. The prostatic chips in each group were examined by 1 histopathologist, who was unaware of the clinical presentation of the patient, for changes of infarction, acute and chronic inflammation, and predominant histological pattern.
There was a higher incidence of glandular pattern in the retention group compared to a stromal pattern in the control group, which was statistically significantly different (p < 0.001). A 5-fold higher incidence of prostatic carcinoma was noted in the acute retention group, which was also statistically significant (p < 0.05).
Prostatic infarction and inflammation had no role in the etiology of acute urinary retention due to BPH.
我们评估急性前列腺梗死和前列腺炎症在良性前列腺增生（BPH）患者引起急性尿潴留中的作用。
进行了一项前瞻性对照临床病理研究，比较35例因BPH继发急性尿潴留的患者与另外35例有症状的BPH患者。所有70例患者均接受经尿道切除术。每组的前列腺组织切片由1名对患者临床表现不知情的组织病理学家检查，以观察梗死、急性和慢性炎症的变化以及主要组织学模式。
与对照组的基质模式相比，潴留组的腺性模式发生率更高，差异有统计学意义（p < 0.001）。急性潴留组前列腺癌的发生率高5倍，差异也有统计学意义（p < 0.05）。
前列腺梗死和炎症在BPH所致急性尿潴留的病因中不起作用。
