Tosti A, Peluso A M, Zucchelli V
Department of Dermatology, University of Bologna, Italy.
Pediatr Dermatol. 1998 Jul-Aug;15(4):259-63. doi: 10.1046/j.1525-1470.1998.1998015259.x.
We report the clinical features and long-term follow-up of 20 pediatric patients with parakeratosis pustulosa (PKP). In eight children PKP was considered as a clinical manifestation of psoriasis. Of these, three children had skin psoriasis at the time of our observation, two developed nail psoriasis, and three developed psoriatic pitting during follow-up. Parakeratosis pustulosa was considered a symptom of allergic contact dermatitis in four patients, whereas atopic dermatitis was possibly responsible for PKP in two patients. A complete recovery from disease was observed in 11 patients. The results of our study suggest that PKP is not a single entity but rather represents a nail symptom that can be produced by several inflammatory diseases, including nail psoriasis, atopic dermatitis, and contact dermatitis.
我们报告了20例儿童脓疱性角质松解症（PKP）患者的临床特征及长期随访情况。在8名儿童中，PKP被认为是银屑病的一种临床表现。其中，在我们观察时，3名儿童有皮肤银屑病，2名出现甲银屑病，3名在随访期间出现银屑病点状凹陷。4例患者的脓疱性角质松解症被认为是过敏性接触性皮炎的症状，而2例患者的PKP可能由特应性皮炎引起。11例患者疾病完全康复。我们的研究结果表明，PKP并非单一疾病，而是一种可由多种炎症性疾病产生的甲部症状，包括甲银屑病、特应性皮炎和接触性皮炎。
