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[一岁以内儿童热性惊厥发病机制中的神经发生因素]

[Neuro-ontogenic factors in the pathogenesis of febrile seizures in children during the first year of life].

作者信息

Novikov A E, Burtsev E M, Karavaev B E

出版信息

Zh Nevrol Psikhiatr Im S S Korsakova. 1998;98(7):12-5.

PMID:9721371
Abstract

Sensomotor development, periods of febrile attacks (FA), spectral EEG characteristics in narrow range of frequency were examined in 12 healthy children and 34 children with FA. There was a correlation between FA debute, relapse and physiologic formation and change of sensomotor rhythm on months 4-5, 7-8, 11-12 of life. The correlation was also established between a decrease of sensomotor reactivity of child, neocortical activation with repeated FA as well as transformation of the attacks' structure. It is suggested that clinical spectrographic regularities observed indicate both activity of pace-maker neurons of pre- and postcentral cortical areas and the disorders of some intercentral relations.

摘要

对12名健康儿童和34名患有热性惊厥(FA)的儿童进行了感觉运动发育、热性惊厥发作期以及窄频率范围内的脑电图频谱特征检查。热性惊厥首次发作、复发与生命第4 - 5个月、7 - 8个月、11 - 12个月时感觉运动节律的生理形成和变化之间存在相关性。儿童感觉运动反应性降低、反复热性惊厥时新皮质激活以及惊厥发作结构的改变之间也建立了相关性。提示所观察到的临床频谱规律既表明中央前和中央后皮质区域起搏神经元的活动,也表明一些中枢间关系的紊乱。

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