Waymire K, Kitzes M, Meredith S, Twiggs G, Berns M W
J Cell Physiol. 1976 Oct;89(2):345-53. doi: 10.1002/jcp.1040890217.
Rat myocardial cells in vitro were irradiated in individual mitochondria with an argon ion laser microbeam. The contractile respone termed fibrillation in single and multicellular groups of both ventricle and auricle cells were compared. Specific correlations were made between fibrillation duration, the number of cells in the group, and the number of times the cells had fibrillated. Correlations were also made for the number of laser shots needed to induce fibrillation and the number of cells in the group. Another set of correlations were made between the pre-irradiation beat frequency and the beat frequency following recovery. Several differences and similarities of the above parameters were detected between auricle and ventricle cells. A comparison of the morphology and ultrastructure of auricle and ventricle cells also revealed significant differences.
体外培养的大鼠心肌细胞，用氩离子激光微束对单个线粒体进行照射。比较了心室和心房细胞的单细胞及多细胞群体中出现的称为颤动的收缩反应。对颤动持续时间、群体中的细胞数量以及细胞颤动的次数之间进行了特定的相关性分析。还对诱发颤动所需的激光照射次数与群体中的细胞数量进行了相关性分析。另外，对照射前的搏动频率与恢复后的搏动频率之间进行了另一组相关性分析。在心房和心室细胞之间检测到上述参数的一些差异和相似之处。对心房和心室细胞的形态和超微结构的比较也显示出显著差异。
