Bamigbade T A, Langford R M
St. Bartholomew's, London.
Hosp Med. 1998 May;59(5):373-6.
Tramadol's two enantiomers produce analgesia, in acute and chronic pain states, by combining synergistically, weak opioid and monoaminergically-mediated mechanisms. Tramadol is interesting, being free of some of the clinically significant side-effects seen with other opioids of comparable efficacy.
曲马多的两种对映体通过协同作用、弱阿片类和单胺能介导机制，在急性和慢性疼痛状态下产生镇痛作用。曲马多很有意思，它没有其他疗效相当的阿片类药物所具有的一些临床上显著的副作用。
