[筛查发现的癌症特征与治疗进展——食管癌]

[Feature of screening-detected cancer and progress of treatment--esophageal cancer].

作者信息

Kouzu T, Suzuki Y, Yoshimura S, Yoshimura N, Hishikawa E, Arima M

机构信息

Dept. of Endoscopic Diagnostics and Therapeutics, Chiba University, Japan.

出版信息

Gan To Kagaku Ryoho. 1998 Aug;25(10):1499-504.

PMID:9725040

Abstract

The recent increase in the detection of esophageal mucosal cancer has been changing the direction of treatment. The rate of esophageal cancer detection in mass screening by X-ray is 0.008%, which is 1/13 that of gastric cancer. Moreover, the rate by endoscopy is higher; the former is 0.1% and the later is 0.6%. Further, endoscopic screening using iodine staining for a high risk group like alcoholism has 3.6% detectability on esophageal cancer and 1.7% on gastric cancer. The rate of cancer-detection of upper intestinal organs comes to 5.35% in all. Most of the esophageal cancer detected by endoscopy is mucosal cancer, which is treatable by endoscopic mucosal resection (EMR). The result of the treatment is 100% 5 year-survival in cases of m1 and 2 esophageal cancer. EMR of esophagus-preserving treatment is truly effective for patients. Endoscopic examination using iodine staining for the high risk group is excellent for mass screening of esophageal cancer.

摘要

近年来，食管黏膜癌检出率的上升正在改变治疗方向。通过X线进行大规模筛查时，食管癌的检出率为0.008%，仅为胃癌检出率的1/13。此外，内镜检查的检出率更高，前者为0.1%，后者为0.6%。此外，对酗酒等高危人群使用碘染色进行内镜筛查，食管癌的检出率为3.6%，胃癌为1.7%。上消化道器官的癌症总检出率为5.35%。内镜检查发现的大多数食管癌为黏膜癌，可通过内镜黏膜切除术（EMR）进行治疗。对于m1和2期食管癌患者，治疗结果为5年生存率达100%。保留食管的EMR治疗对患者确实有效。对高危人群使用碘染色进行内镜检查，非常适合食管癌的大规模筛查。