儿童眼球突出的病因

Aetiology of childhood proptosis.

作者信息

Sindhu K, Downie J, Ghabrial R, Martin F

机构信息

Department of Ophthalmology, New Childrens Hospital, Westmead, Australia.

出版信息

J Paediatr Child Health. 1998 Aug;34(4):374-6. doi: 10.1046/j.1440-1754.1998.00243.x.

DOI:10.1046/j.1440-1754.1998.00243.x

PMID:9727182

Abstract

OBJECTIVE

To retrospectively analyse causes of childhood proptosis and their investigations and treatment.

METHODOLOGY

The records of children under 15 years of age presenting with proptosis to The Children's Hospital, Camperdown, Sydney, were reviewed for the period 1983-93 inclusive.

RESULTS

Fifty-seven cases of proptosis were found. In order of frequency the causes were; orbital cellulitis 22, thyroid eye disease 8, optic nerve +/- optic chiasm glioma 8, orbital rhabdomyosarcoma 7, metastatic neuroblastoma 4, orbital neurofibroma 3, orbital haemangioma 2, metastatic Ewing's sarcoma 2 and orbital dermoid cyst 1. Treatment depended on the cause (antibiotics, antithyroid drugs, chemotherapy, radiotherapy, surgery) and was multidisciplinary.

CONCLUSIONS

The most common cause of proptosis in children presenting to The Children's Hospital, Camperdown, Sydney, was infective orbital cellulitis. The most useful initial investigation was an orbital computed tomography scan. Treatment depended on the cause of the proptosis and was multidisciplinary.

摘要

目的

回顾性分析儿童眼球突出的病因及其检查与治疗情况。

方法

对1983年至1993年期间（含1993年）就诊于悉尼坎珀当儿童医院的15岁以下眼球突出患儿的病历进行回顾。

结果

共发现57例眼球突出病例。按发生频率排序，病因依次为：眼眶蜂窝织炎22例，甲状腺眼病8例，视神经及/或视交叉神经胶质瘤8例，眼眶横纹肌肉瘤7例，转移性神经母细胞瘤4例，眼眶神经纤维瘤3例，眼眶血管瘤2例，转移性尤因肉瘤2例，眼眶皮样囊肿1例。治疗取决于病因（抗生素、抗甲状腺药物、化疗、放疗、手术），且为多学科综合治疗。