Wessel J, Holbach L
Augenklinik, Universitätsklinik Erlangen, Schwabachanlage 6, 91054, Erlangen, Deutschland.
Ophthalmologe. 2012 May;109(5):491-4. doi: 10.1007/s00347-011-2491-x.
Hemorrhage into an orbital lymphangioma can cause acute proptosis. A lymphangioma must be distinguished from acute threatening causes of rapidly developing proptosis in childhood, such as orbital cellulitis or malignant tumors (rhabdomyosarcoma). Imaging (magnetic resonance imaging, ultrasound, computed tomography) and histopathological evaluation are required for the final diagnosis. Immunohistochemical staining of lymphatic vessels with podoplanin can be useful for confirmation of the diagnosis.
眼眶淋巴管瘤内出血可导致急性眼球突出。必须将淋巴管瘤与儿童期迅速发展的眼球突出的急性威胁性病因相鉴别,如眼眶蜂窝织炎或恶性肿瘤(横纹肌肉瘤)。最终诊断需要影像学检查(磁共振成像、超声、计算机断层扫描)和组织病理学评估。用足板蛋白对淋巴管进行免疫组织化学染色有助于确诊。