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变应性支气管肺曲霉病

Allergic bronchopulmonary aspergillosis.

作者信息

Shah A

机构信息

Department of Clinical Research, Vallabhbhai Patel Chest Institute, University of Delhi.

出版信息

Indian J Chest Dis Allied Sci. 1998 Jan-Mar;40(1):41-54.

PMID:9727282
Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is an immunologically mediated lung disease which occurs predominantly in patients with asthma, and is caused by hypersensitivity to colonized Aspergillus fumigatus. It is a chronic, relapsing disorder which can clinically range from mild asthma to fibrotic lung disease. The immunopathogenesis of the disease is not clearly understood. Early diagnosis and aggressive therapy with oral corticosteroids can prevent the development of fibrotic lung disease and are therefore, the cornerstone of management.

摘要

变应性支气管肺曲霉菌病(ABPA)是一种免疫介导的肺部疾病,主要发生于哮喘患者,由对寄生于肺部的烟曲霉菌过敏所致。它是一种慢性复发性疾病,临床症状从轻度哮喘到肺纤维化不等。该疾病的免疫发病机制尚不清楚。早期诊断并积极采用口服糖皮质激素治疗可预防肺纤维化的发生,因此是治疗的基石。

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