Grigor'ev M E, Mazo E B, Chekhonin V P
Urol Nefrol (Mosk). 1998 Jul-Aug(4):33-7.
Analysis of the changes in the levels of total prostatic specific antigen (t-PSA) in patients with benign prostatic hyperplasia (BPH) shows that the patient's age, size of the prostatic gland and chronic bacterial prostatitis influence the levels of t-PSA but have no effect on the levels of PSA-ACT. The relationship between the levels of t-PSA and age in BPH patients is explained by growing mass of benign hyperplasia causing mechanical load on the intact prostatic tissue. The maximal concentration of t-PSA of 8.7 +/- 1.22 ng/ml was observed in BPH patients at the age of 61-70 years. BPH stages, chronic pyelonephritis, chronic non-bacterial prostatitis, chronic renal failure are not essential for t-PSA and PSA-ACT and can be neglected in interpretation of t-PSA values in BPH patients.
对良性前列腺增生（BPH）患者总前列腺特异性抗原（t-PSA）水平变化的分析表明，患者的年龄、前列腺大小和慢性细菌性前列腺炎会影响t-PSA水平，但对PSA-ACT水平没有影响。BPH患者中t-PSA水平与年龄之间的关系可以解释为良性增生的质量增加对完整前列腺组织造成机械负荷。在61至70岁的BPH患者中观察到t-PSA的最大浓度为8.7±1.22 ng/ml。BPH分期、慢性肾盂肾炎、慢性非细菌性前列腺炎、慢性肾衰竭对t-PSA和PSA-ACT并不重要，在解释BPH患者的t-PSA值时可以忽略不计。
