Davis R E, Calder J S, Curnow D H
Pathology. 1976 Apr;8(2):151-6. doi: 10.3109/00313027609094441.
Serum pyridoxal and folate concentrations were measured in 518 diabetics. There were 185 males and 333 females. The level of pyridoxal was significantly lower in the diabetics when compared with 371 'healthy' controls and 25% had levels below the lower limit of the normal range. No significant difference was observed between diabetics being treated by diet alone, oral hypoglycaemics or insulin. Only 20 patients had a reduced serum folate level and in 6 this was accompanied by a low pyridoxal concentration. The results suggest that diabetics may have an increased demand for pyridoxal.
对518名糖尿病患者测定了血清吡哆醛和叶酸浓度。其中男性185名，女性333名。与371名“健康”对照者相比，糖尿病患者的吡哆醛水平显著降低，25%的患者水平低于正常范围下限。仅采用饮食治疗、口服降糖药或胰岛素治疗的糖尿病患者之间未观察到显著差异。只有20例患者血清叶酸水平降低，其中6例同时伴有吡哆醛浓度降低。结果表明，糖尿病患者对吡哆醛的需求量可能增加。
