Davis R E, McCann V J, Ormonde N W, Goodwin C S
Pathology. 1981 Jul;13(3):587-91. doi: 10.3109/00313028109059076.
Of 1017 patients admitted to the Royal Perth Hospital Diabetic Survey 142 were found to have significant bacteriuria. In these bacteriuric patients serum pyridoxal concentrations were significantly reduced (P = less than 0.001) when compared with 142 diabetic patients matched for age (+/- 5 years) and sex but without infection of the urinary tract. Measurements were repeated up to 6 mth after antibacterial treatment and serum pyridoxal concentrations were still low. Pyridoxal has a role in immunological competence, and it is possible that the increased incidence of urinary tract infection in patients with diabetes reflects impaired immunological competence due to pyridoxal deficiency.
在皇家珀斯医院糖尿病调查收治的1017例患者中，发现142例有显著菌尿。与142例年龄匹配（±5岁）、性别相同但无尿路感染的糖尿病患者相比，这些菌尿患者的血清吡哆醛浓度显著降低（P＜0.001）。抗菌治疗后长达6个月重复进行测量，血清吡哆醛浓度仍很低。吡哆醛在免疫能力方面发挥作用，糖尿病患者尿路感染发生率增加可能反映了因吡哆醛缺乏导致的免疫能力受损。
