Makridis S D, Mellado J R, Freedman A L, Salkin L M, Stein M D, Leal K, Miller A S
Department of Periodontology, Temple University School of Dentistry, Philadelphia, Pennsylvania 19140, USA.
Int J Periodontics Restorative Dent. 1998 Jun;18(3):292-8.
All oral squamous cell carcinomas were retrieved from the files of Temple University's Oral Pathology Laboratory from 1967 through 1994 for a clinicopathologic study of those occurring on the gingiva. A total of 1,193 cases had sufficient data for tabulation and statistical analysis, of which 300 (25%) arose on the gingiva or alveolar ridge. The largest number of these cases (211/300) occurred on the mandibular gingiva or alveolar ridge. The mean age of the patients was 66.66 years, with males accounting for 57% of cases. Many case comparison analyses of oral squamous cell carcinomas do not separate oral subsites or specifically address carcinoma of the gingiva. The results were compared with other published series and suggest that further studies are needed because of the wide range of reported figures on the incidence of gingival squamous cell carcinomas.
所有口腔鳞状细胞癌均取自天普大学口腔病理学实验室1967年至1994年的档案，用于对发生在牙龈上的此类癌症进行临床病理研究。共有1193例病例有足够的数据进行列表和统计分析，其中300例（25%）发生在牙龈或牙槽嵴。这些病例中数量最多的（211/300）发生在下颌牙龈或牙槽嵴。患者的平均年龄为66.66岁，男性占病例的57%。许多口腔鳞状细胞癌的病例对照分析并未区分口腔亚部位，也未专门针对牙龈癌。研究结果与其他已发表的系列研究进行了比较，结果表明，由于牙龈鳞状细胞癌发病率的报告数据差异很大，因此需要进一步研究。
