Kabalin J N, Gilling P J, Fraundorfer M R
Scottsbluff Urology Associates, Regional West Medical Center, Nebraska, USA.
J Clin Laser Med Surg. 1998 Feb;16(1):21-7. doi: 10.1089/clm.1998.16.21.
The authors review the current knowledge regarding the application of the Holmium: YAG laser for prostatectomy.
Conventional surgical therapies for benign prostatic hyperplasia (BPH) are effective but associated with relatively high morbidity. Laser prostatectomy, using either Neodymium:YAG or potassium-titanyl-phosphate lasers, has emerged as a new and much safer operative approach to relieve symptoms of benign prostatic hyperplasia. However, these laser wavelengths possess key disadvantages that have limited their acceptability and dissemination in everyday urologic practice.
THE authors review their own extensive experience in the development of clinical application of Holmium: YAG laser technology for prostatectomy, as well as the published reports in the current medical literature now dealing with this subject.
In multiple clinical trials, Holmium:YAG laser resection of the prostate has proven efficacious in relieving symptomatic BPH. Both objective urodynamic measures of voiding outcomes and symptomatic improvement have been shown to be equivalent to standard electrocautery resection of the prostate. At the same time, these studies have demonstrated the superior safety and hemostasis of Holmium:YAG laser prostatectomy compared to electrocautery resection, similar to prior laser prostatectomy procedure. Unlike prior forms of laser prostatectomy, Holmium:YAG laser resection of the prostate acutely removes all obstructing prostate tissue, so that the postoperative catheterization requirement is typically only overnight and improvement in voiding is immediate. Current operative techniques and the latest technological developments to facilitate Holmium:YAG laser prostatectomy are described.
Holmium: YAG laser prostatectomy combines the best features of prior laser prostatectomy technologies, including minimal complications and morbidity, with the efficacy and immediacy of voiding outcomes associated with conventional electrocautery resection of the prostate.
作者回顾了有关钬激光在前列腺切除术中应用的当前知识。
良性前列腺增生(BPH)的传统手术治疗有效,但发病率相对较高。使用钕:钇铝石榴石激光或磷酸钛钾激光的激光前列腺切除术已成为一种新的、更安全的手术方法,用于缓解良性前列腺增生的症状。然而,这些激光波长存在关键缺点,限制了它们在日常泌尿外科实践中的可接受性和推广。
作者回顾了他们自己在钬激光技术用于前列腺切除术临床应用开发方面的丰富经验,以及当前医学文献中关于该主题的已发表报告。
在多项临床试验中,钬激光前列腺切除术已被证明对缓解有症状的BPH有效。排尿结果的客观尿动力学指标和症状改善均已显示与标准前列腺电切术相当。同时,这些研究表明,与电切术相比,钬激光前列腺切除术具有更高的安全性和止血效果,与先前的激光前列腺切除术类似。与先前的激光前列腺切除术形式不同,钬激光前列腺切除术能立即切除所有阻塞性前列腺组织,因此术后导尿通常只需 overnight(此处原文可能有误,推测是overnight,意为过夜),排尿立即改善。描述了当前促进钬激光前列腺切除术的手术技术和最新技术发展。
钬激光前列腺切除术结合了先前激光前列腺切除术技术的最佳特点,包括并发症和发病率最低,以及与传统前列腺电切术相关的排尿效果的有效性和即时性。