Dean R C, Moul J W
Department of Surgery, Walter Reed Army Medical Center, Washington, DC, USA.
Urol Clin North Am. 1998 Aug;25(3):365-73. doi: 10.1016/s0094-0143(05)70027-6.
Potential tumor markers for testis cancer have become numerous with the new molecular techniques available. New protein markers have been evaluated, and histologic factors have shown correlations with stage of disease. Cytogenetic analysis studies have also shown associations with stage progression. Chromosomal markers, oncogenes, and tumor suppressor genes are possible candidates for tumor markers. These new potential tumor markers may become as commonplace as the established markers and may enhance diagnosis, staging, and treatment of testis cancer.
随着新的分子技术的出现，睾丸癌潜在的肿瘤标志物数量众多。新的蛋白质标志物已得到评估，并且组织学因素已显示出与疾病分期相关。细胞遗传学分析研究也显示出与疾病进展阶段有关联。染色体标志物、癌基因和肿瘤抑制基因都可能是肿瘤标志物的候选者。这些新的潜在肿瘤标志物可能会像已确立的标志物一样常见，并可能会提高睾丸癌的诊断、分期和治疗水平。
