Turek P J, Lowther D N, Carroll P R
Department of Urology, University of California San Francisco, USA.
Urol Clin North Am. 1998 Aug;25(3):517-31. doi: 10.1016/s0094-0143(05)70041-0.
Although a curable malignancy, testis cancer and its treatment have unique associated morbidities that largely affect reproductive dysfunction. In this focused review, the factors that contribute to infertility in men with testis cancer are outlined. The treatment-specific risks to fertility that accompany cancer management are also discussed. Contemporary methods of overcoming infertility in testis cancer patients are addressed, and several exciting and promising experimental approaches to the preservation or restoration of fertility for men with testis cancer are presented.
睾丸癌虽是一种可治愈的恶性肿瘤,但其及其治疗具有独特的相关发病率,很大程度上会影响生殖功能障碍。在这篇重点综述中,概述了导致睾丸癌男性不育的因素。还讨论了癌症治疗过程中伴随的特定生育风险。探讨了当代克服睾丸癌患者不育问题的方法,并介绍了几种用于保留或恢复睾丸癌男性生育能力的令人兴奋且有前景的实验方法。