Giwercman A, Petersen P M
University Department of Urology, Malmö University Hospital, Malmö, SE, 20502, Sweden.
Baillieres Best Pract Res Clin Endocrinol Metab. 2000 Sep;14(3):453-71. doi: 10.1053/beem.2000.0091.
An increasing proportion of boys and young men with cancer will survive their disease and desire fertility. Unfortunately, the cancer treatment, and in some cases the malignant disease itself, may have a negative and permanent impact on the individual's fertility potential. This effect is highly dependent on the type and dose of therapy as well as the age at which it has been given. Basic knowledge in this field is necessary to enable oncologists and fertility specialists to counsel these patients about their fertility prospects and, if appropriate, advise them to take precautions (e.g. the cryopreservation of semen) to safeguard their fertility. Another aspect of the relationship between cancer and infertility is the possibility that men with testicular dysfunction may have an increased risk of testicular cancer. Screening for early testicular malignancy may therefore be advisable in some groups of men with poor semen quality.
越来越多患癌症的男孩和年轻男性将战胜疾病并渴望生育。不幸的是，癌症治疗，在某些情况下恶性疾病本身，可能会对个体的生育潜力产生负面且永久性的影响。这种影响高度依赖于治疗的类型和剂量以及接受治疗时的年龄。该领域的基础知识对于肿瘤学家和生育专家为这些患者提供有关其生育前景的咨询意见，并在适当时建议他们采取预防措施（例如冷冻精液）以保护生育能力而言是必要的。癌症与不育之间关系的另一个方面是，患有睾丸功能障碍的男性可能患睾丸癌的风险增加。因此，对于精液质量较差的某些男性群体，建议进行早期睾丸恶性肿瘤筛查。
