Sharma V K, Bapuraj J R, Mann S B, Kaur I, Kumar B
Department of Dermatology, Venereology & Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Int J Lepr Other Mycobact Dis. 1998 Jun;66(2):201-7.
Twenty patients (18 males, 2 females) with lepromatous leprosy and 10 age- and sex-matched controls were subjected to computed tomographic (CT) scans of the paranasal sinuses (PNS). The mean bacterial (BI) and morphological indexes were 3.4+ and 1%, respectively. Nasal symptoms were present in nine (45%) patients; 15 (75%) out of 20 patients showed significant abnormalities on CT scans of the PNS compared to none of the 10 controls. The maxillary and ethmoid sinuses were affected in 11 (55%) patients each, followed by the sphenoid sinus in four (20%) patients. Frontal sinus involvement was least frequent, only one (5%) patient showed CT changes. Mucosal thickening was the most common finding followed by soft-tissue densities and, rarely, a fluid level was seen in the PNS. Involvement of the PNS correlated with a high BI of 4+ or more (75% vs 37.5%). Paranasal sinus involvement is an integral part of lepromatous leprosy since histological involvement was present even when the CT scan was apparently normal.
对20例瘤型麻风患者（18例男性，2例女性）和10例年龄及性别匹配的对照者进行了鼻窦计算机断层扫描（CT）。细菌指数（BI）和形态学指数的平均值分别为3.4+和1%。9例（45%）患者有鼻部症状；20例患者中有15例（75%）鼻窦CT扫描显示明显异常，而10例对照者均无异常。上颌窦和筛窦各有11例（55%）患者受累，其次是蝶窦，有4例（20%）患者受累。额窦受累最少见，仅1例（5%）患者CT有改变。黏膜增厚是最常见的表现，其次是软组织密度影，鼻窦内很少见液平面。鼻窦受累与BI为4+或更高相关（75%对37.5%）。鼻窦受累是瘤型麻风的一个组成部分，因为即使CT扫描明显正常，组织学上也存在受累情况。
