Demyttenaere K, De Fruyt J, Sienaert P
Department of Psychiatry, University Hospitals Gasthuisberg, Leuven, Belgium.
Int Clin Psychopharmacol. 1998 Jul;13 Suppl 6:S35-41. doi: 10.1097/00004850-199807006-00007.
Relatively little is known about the sexual side-effects of psychotropic drugs, probably due to the taboos surrounding discussion of sexual matters. However, there is a growing interest in this topic. The antidepressants are probably the most widely studied class of psychotropic drug and evidence suggests that all commonly used classes are associated with some sexual side-effects. However, there may well be differences between the effects of different drugs in the same class. The study of sexual side-effects in bipolar patients taking mood stabilizers is complicated by the existence of numerous confounding variables and only limited data are currently available on the sexual side-effects of benzodiazepines and antipsychotics. It is also important to take into account a number of methodological considerations when interpreting data on the sexual side-effects of psychotropic drugs.
人们对精神药物的性副作用了解相对较少,这可能是由于围绕性问题讨论存在诸多禁忌。然而,这个话题正越来越受到关注。抗抑郁药可能是研究最为广泛的一类精神药物,有证据表明,所有常用类别都与某些性副作用有关。然而,同一类别的不同药物的作用可能存在很大差异。服用心境稳定剂的双相情感障碍患者的性副作用研究因存在众多混杂变量而变得复杂,目前关于苯二氮䓬类药物和抗精神病药物的性副作用仅有有限的数据。在解释精神药物性副作用的数据时,考虑一些方法学因素也很重要。