Hitosugi M, Maruyama K, Takatsu A
Department of Forensic Medicine, Jikei University, School of Medicine, Tokyo, Japan.
Int J Legal Med. 1998;111(5):265-6. doi: 10.1007/s004140050166.
Five elderly persons with senile dementia accidentally ingested Hoesmin, a 10% aqueous solution of benzalkonium chloride (BAC). The condition of one patient, an 84-year-old woman whose lips and oral cavity became erythematous, gradually deteriorated. Although gastric lavage was performed, the patient died 3 h after ingestion of Hoesmin. Autopsy revealed corrosive changes of the mucosal surfaces of the tongue, pharynx, larynx, esophagus and stomach which may have come in contact with BAC. In addition, BAC was detected in the serum. We conclude that the patient died of BAC poisoning. Fatal BAC poisoning is rare and autopsy findings in only a few cases of BAC poisoning have been reported. Our findings emphasize the risk of oral ingestion of BAC.
五名患有老年痴呆症的老年人意外摄入了霍斯明（Hoesmin），一种10%的苯扎氯铵（BAC）水溶液。其中一名患者，一名84岁的女性，嘴唇和口腔出现红斑，病情逐渐恶化。尽管进行了洗胃，但该患者在摄入霍斯明3小时后死亡。尸检显示，舌头、咽部、喉部、食管和胃的黏膜表面可能与BAC接触的部位出现了腐蚀性变化。此外，在血清中检测到了BAC。我们得出结论，该患者死于BAC中毒。致命的BAC中毒很罕见，仅有少数BAC中毒病例的尸检结果被报道。我们的发现强调了口服BAC的风险。
