Nuñez A, Buño W, Reinoso-Suárez F
Departamento de Morfología, Facultad de Medicina, Universidad Autónoma de Madrid, Arzobispo Morcillo s/n., 28029, Madrid, Spain.
Brain Res. 1998 Aug 31;804(1):144-8. doi: 10.1016/s0006-8993(98)00681-7.
The actions of neurotransmitters involved in the sleep-wakefulness cycle on neurons located in the ventral part of the oral pontine tegmentum were studied in a rat brain-slice preparation. Results show that glutamate and histamine evoke depolarizations and spike firing while serotonin and gamma-aminobutyric acid evoke hyperpolarizations. The excitatory and inhibitory actions of these neurotransmitters increase pontine neuron activity during the conditions occurring during paradoxical sleep.
在大鼠脑片制备中，研究了参与睡眠 - 觉醒周期的神经递质对位于脑桥被盖腹侧部神经元的作用。结果表明，谷氨酸和组胺可引起去极化和动作电位发放，而血清素和γ-氨基丁酸则引起超极化。在异相睡眠期间出现的条件下，这些神经递质的兴奋和抑制作用会增加脑桥神经元的活动。
