Kayes J M, Clark S E
Department of Biology, University of Michigan, Ann Arbor, MI 48109-1048, USA.
Development. 1998 Oct;125(19):3843-51. doi: 10.1242/dev.125.19.3843.
Mutations at the CLAVATA2 (CLV2) locus of Arabidopsis result in enlarged shoot and flower meristems, as well as alterations in the development of the gynoecia, flower pedicels, and stamens. The shoot and flower meristem phenotypes of clv2 mutants are similar to weak clv1 and clv3 mutants. We present genetic analysis that CLV2 may function in the same pathway as CLV1 and CLV3 in the regulation of meristem development, but function separately in the regulation of organ development. We also present evidence that clv2 phenotypes are altered when the mutants are grown under short-day light conditions. These alterations include flower-to-shoot transformations, as well as a nearly complete suppression of the flower phenotypes, indicating that the requirement for CLV2 changes in response to different physiological conditions. The stm-1 mutation dominantly suppresses clv2, and clv2 mutations suppress the strong stm-1 allele, but not the weak stm-2 allele.
拟南芥CLAVATA2（CLV2）基因座的突变会导致茎尖和花分生组织增大，以及雌蕊、花梗和雄蕊发育的改变。clv2突变体的茎尖和花分生组织表型与弱clv1和clv3突变体相似。我们进行了遗传分析，结果表明CLV2在分生组织发育调控中可能与CLV1和CLV3处于同一途径，但在器官发育调控中发挥独立作用。我们还提供了证据表明，当突变体在短日照条件下生长时，clv2的表型会发生改变。这些改变包括花向茎的转变，以及花表型几乎完全受到抑制，这表明对CLV2的需求会因不同的生理条件而改变。stm - 1突变显性抑制clv2，而clv2突变抑制强stm - 1等位基因，但不抑制弱stm - 2等位基因。
