Gyenes V, Szabó G, Velich N
Semmelweis Orvostudományi Egyetem Szájsebészeti és Fogászati Klinika, Budapest.
Fogorv Sz. 1998 Aug-Sep;91(8-9):257-60.
In 8 cases of maxillary and mandibular osteomyelitis which had failed to respond to traditional surgical and medicinal methods of treatment, a significant improvement could be achieved (in 7 of the 8 cases) by applying an intra-arterial clindamycin therapy. Treatment was carried out similar to the intra-arterial cytostatic perfusion treatment of tumors in the head and neck areas. Clindamycin was administered in daily dosages of 900 mg over a period of 8-23 days.
8例上颌骨和下颌骨骨髓炎患者,采用传统手术和药物治疗均未见效,应用动脉内克林霉素治疗后(8例中有7例)取得了显著改善。治疗方法与头颈部肿瘤的动脉内细胞毒性灌注治疗相似。克林霉素的给药剂量为每日900毫克,持续8 - 23天。