Stephen K W, Macpherson L M, Gorzó I, Gilmour W H
University of Glasgow, School of Dentistry Department of Dental Public Health.
Fogorv Sz. 1998 Aug-Sep;91(8-9):275-80.
Salt fluoridation is effective at inhibiting caries, but fluorosis prevalence data are different. The purpose was to undertake a blind caries and tooth mottling study of 14-yrs-olds from S. E. Hungary who did (Test) or did not (Control) live, until 1985, in a 350 pp F-/kg salt fluoridated area during their early years of life. In Szeged, blind clinical and anterior tooth-mottling, radiographic and photographic recording of 49 previously salt-fluoridated and 59 non-salt-fluoridated subjects were undertaken by one examiner. In Glasgow, four dental and two lay staff scored the projected 35 mm colour transparencies of each pupil's teeth (13-23), for tooth mottling. Mean DMFS scores were 9.18 (SD = 10.72) and 4.51 (SD = 6.4) for Test and Control users respectively (p < 0.01). Clinically three Test children had fluorosis of 10 teeth, with 8 teeth in two Controls. In a sole Test case was "fluorosis" photographic unanimity obtained, and non-unanimous "possible fluorosis" was recorded by two-four 'jurors' for only three other Test and two Control subjects. No evidence was found that significant fluorosis resulted in subjects exposed previously to 350 ppm F-/kg salt early in life, but no caries benefit was demonstrated after the 11.5-yr salt fluoridation gap. These data emphasize (a) the superiority of substained community-delivered fluoridation, and (b) the need to maintain constant fluoride delivery to tooth surfaces, and certainly well beyond 10 years of age.
食盐氟化在预防龋齿方面很有效，但氟斑牙患病率数据却有所不同。目的是对匈牙利东南部14岁青少年进行一项龋齿和牙齿斑纹的盲法研究，这些青少年在1985年前的幼年时期，有的（试验组）生活在氟含量为350 ppm F⁻/kg的食盐氟化地区，有的（对照组）则没有。在塞格德，由一名检查者对49名曾接受食盐氟化的受试者和59名未接受食盐氟化的受试者进行了盲法临床检查、上前牙斑纹检查、影像学和摄影记录。在格拉斯哥，四名牙科工作人员和两名非专业人员对每个学生牙齿（13 - 23颗）的35毫米彩色幻灯片进行评分，以评估牙齿斑纹情况。试验组和对照组使用者的平均DMFS得分分别为9.18（标准差 = 10.72）和4.51（标准差 = 6.4）（p < 0.01）。临床上，试验组有3名儿童的10颗牙齿出现氟斑牙，对照组有2名儿童的8颗牙齿出现氟斑牙。在试验组中，仅1例“氟斑牙”在摄影判断上达成一致，另外只有3名试验组受试者和2名对照组受试者被两至四名“评审员”记录为非一致的“可能氟斑牙”。没有发现证据表明早年接触过350 ppm F⁻/kg食盐的受试者出现了严重氟斑牙，但在食盐氟化中断11.5年后，未显示出对龋齿的预防效果。这些数据强调了（a）持续社区提供氟化措施的优越性，以及（b）需要持续向牙齿表面提供氟化物，且肯定要超过10岁。
