Pukkala E
Finnish Cancer Registry, Helsinki, Finland.
J Occup Environ Med. 1998 Aug;40(8):675-9. doi: 10.1097/00043764-199808000-00003.
Cancer incidence between 1971 and 1994 was studied in a cohort of 7,512 men and 1,942 women who had been employed for at least 3 months in a Finnish enterprise that was primarily active in oil refining. The expected numbers of cancer cases were based on the national incidence rates. The standardized incidence ratios (SIR) for overall cancer after 5 years at work was decreased by 12% because of a significant deficit from cancer of the lung in oil refineries (SIR, 0.3; 95% confidence interval [95% CI], 0.1-0.6). There was a significant excess of kidney cancer in males, which was highest among men with at least 5 years of employment in oil refineries (SIR 2.8; 95% CI, 1.6-4.7). Male blue-collar workers had a twofold risk of non-Hodgkin's lymphoma and non-melanocytic skin cancer. Occupational exposure to gasoline may be associated with increased risk of cancer of the kidney.
对芬兰一家主要从事炼油业务的企业中至少工作了3个月的7512名男性和1942名女性队列进行了1971年至1994年期间癌症发病率的研究。癌症病例的预期数量基于全国发病率。工作5年后总体癌症的标准化发病率(SIR)降低了12%,原因是炼油厂肺癌显著不足(SIR,0.3;95%置信区间[95%CI],0.1 - 0.6)。男性肾癌显著增多,在炼油厂至少工作5年的男性中最高(SIR 2.8;95%CI,1.6 - 4.7)。男性蓝领工人患非霍奇金淋巴瘤和非黑素细胞性皮肤癌的风险是两倍。职业性接触汽油可能与肾癌风险增加有关。