Wunderlich R P, Armstrong D G, Husain K, Lavery L A
Department of Orthopaedics, University of Texas Health Science Center at San Antonio, USA.
Adv Wound Care. 1998 May-Jun;11(3):123-8.
Although the importance of distal symmetric sensorimotor polyneuropathy as a risk factor for diabetic foot ulceration has been known for decades, attempts to identify the elusive point that defines loss of protective sensation have been futile. This manuscript will review the epidemiology and pathogenesis of peripheral neuropathy, discuss commonly used screening tools, and review recently reported data that more sharply define loss of protective sensation on the long spectrum of neuropathy.
尽管远端对称性感觉运动性多发性神经病变作为糖尿病足溃疡危险因素的重要性已为人所知数十年，但试图确定界定保护性感觉丧失的难以捉摸的临界点的尝试一直徒劳无功。本文将回顾周围神经病变的流行病学和发病机制，讨论常用的筛查工具，并回顾最近报道的数据，这些数据更清晰地界定了在神经病变的漫长范围内的保护性感觉丧失。
