Shinozaki T, Watanabe H, Aoki J, Fukuda T, Shirakura K, Takagishi K
Department of Orthopedic Surgery, Gunma University Faculty of Medicine, Maebashi, Japan.
Skeletal Radiol. 1998 Jul;27(7):359-64. doi: 10.1007/s002560050398.
This report describes subcutaneous sarcoidosis, focusing on the radiological and magnetic resonance (MR) features of the disease.
The cases of four patients (one male and three female, age range 36-75 years) who had subcutaneous sarcoidosis with no other organs affected were reviewed. Lesions were nodular in two cases, and in the other two were diffuse.
Computed tomography (CT) demonstrated a well-defined, homogeneous, and enhanced lesion in the nodular cases. However, in the diffuse cases, CT showed a heterogeneous, honeycomb-like appearance and little enhancement. Angiography showed a fine stain in the arterial phase. MR imaging of the nodular lesions was homogeneous with a signal intensity similar to muscle on T1-weighted images but heterogeneous with a higher signal than muscle on T2-weighted images. Diffuse lesions showed a striped or mesh pattern with intermediate signal intensity on both T1- and T2-weighted images. Contrast-enhanced MR images showed slight enhancement.
Subcutaneous sarcoidosis should be considered in the differential diagnosis when a patient presents with the radiological and MR features described.
本报告描述皮下结节病，重点关注该疾病的放射学和磁共振（MR）特征。
回顾了4例皮下结节病患者（1例男性，3例女性，年龄范围36 - 75岁），这些患者无其他器官受累。病变在2例中为结节状，在另外2例中为弥漫性。
计算机断层扫描（CT）显示结节状病例中有边界清晰、均匀且强化的病变。然而，在弥漫性病例中，CT显示为不均匀的蜂窝状外观且强化不明显。血管造影显示动脉期有细染色。结节状病变的MR成像在T1加权图像上与肌肉信号强度相似，呈均匀性，但在T2加权图像上不均匀，信号高于肌肉。弥漫性病变在T1加权和T2加权图像上均显示为条纹状或网状图案，信号强度中等。对比增强MR图像显示轻度强化。
当患者出现所述的放射学和MR特征时，鉴别诊断应考虑皮下结节病。
