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[不同激素状态下大鼠肝脏脂质中1-C14棕榈酸的掺入]

[Incorporation of 1-C14 palmitic acid into liver lipids of rats in different hormanal states].

作者信息

De Gandarias J M, Lacort M, Fernández B, Ainz F, Goiriena De Gandarias J J, Rabanal S, Pamo J M

出版信息

Rev Iber Endocrinol. 1976;23(136):357-70.

PMID:973082
Abstract

Adrenalectomy and/or cortisol-induced variations in the in vivo and in vitro incorporation of 14C-palmitic acid 1 into the different fractions of rat liver lipids were studied. The different fatty acids incorporations follow analogous patterns in every hormonal state in vitro. Incorporation rate is faster in normal animals, but adrenalectomy or the administration of cortisol produces a marded delay. Cortisol does not modify the anomalism observed in the adrenoprival state. In vivo, the incorporation of palmitic acid into the different liver lipids--for the same hormonal state--does not follow the same pattern.

摘要

研究了肾上腺切除术和/或皮质醇诱导的大鼠肝脂质不同组分中14C-棕榈酸1体内外掺入的变化。在体外,不同脂肪酸的掺入在每种激素状态下遵循类似的模式。正常动物的掺入率更快,但肾上腺切除术或皮质醇给药会导致明显延迟。皮质醇不会改变肾上腺功能缺失状态下观察到的异常。在体内,对于相同的激素状态,棕榈酸掺入不同肝脂质的情况并不遵循相同的模式。

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