Suppr超能文献

因哮喘和慢性阻塞性肺疾病前往急诊室就诊人群的死亡率的性别差异。

Sex differences in mortality of people who visited emergency rooms for asthma and chronic obstructive pulmonary disease.

作者信息

Sunyer J, Antó J M, McFarlane D, Domingo A, Tobías A, Barceló M A, Múnoz A

机构信息

Units of Respiratory and Environmental Research, and Health Services Research, Institut Municipal d'Investigació Mèdica (IMIM), Barcelona, Catalonia, Spain.

出版信息

Am J Respir Crit Care Med. 1998 Sep;158(3):851-6. doi: 10.1164/ajrccm.158.3.9801093.

Abstract

We assess the sex differences in mortality in a population-based cohort of those Barcelona residents older than 14 yr of age who received emergency room services (ERS) for either chronic obstructive pulmonary disease (COPD) or asthma, during the period from 1985 to 1989. Vital status was followed to the end of 1995. A total of 15,517 individuals, 9,918 males and 5,599 females were included in the study. Asthma was diagnosed in 16% of males and 53% of females. Overall, 50% of males and 30% of females died during the follow-up period. The mortality rates in both males and females who visited emergency rooms for COPD or asthma were significantly higher than the expected rates in the general population. These relative increases in the mortality rates were significantly higher in females than in males for both causes of death, COPD (age-adjusted female/male ratio = 2.39), and asthma (ratio = 3.95). However, survival was better in females than males among individuals in the study. The higher fatality in males than females was observed for all causes of death, all respiratory causes, and COPD (risk ratio among patients with COPD = 0.42, 0.29-0.59, and among patients with asthma = 0.11, 0.02-0.60), but not for asthma. Mortality for asthma was higher in females with a diagnosis of COPD (2.79, 1.52-5.13), but it was not different among individuals in whom asthma was diagnosed (1.02, 0.56-1.87). Greater severity of COPD in males than in females could explain a higher risk of dying for all respiratory causes and COPD in males. The increased risk of asthma death in females may be due to problems of coding the term "asthma" in death certificates. The higher rates in females than in males when comparing with the general population, may be an expression of a greater similarity in risk factors, such as smoking, in our population than in males and females of the general population.

摘要

我们评估了1985年至1989年期间,巴塞罗那14岁以上因慢性阻塞性肺疾病(COPD)或哮喘接受急诊服务(ERS)的居民群体中的死亡率性别差异。对这些居民的生命状态进行随访至1995年底。该研究共纳入15517人,其中男性9918人,女性5599人。男性中16%被诊断为哮喘,女性中53%被诊断为哮喘。总体而言,随访期间50%的男性和30%的女性死亡。因COPD或哮喘就诊急诊室的男性和女性死亡率均显著高于普通人群的预期死亡率。两种死因(COPD和哮喘)导致的死亡率相对增加在女性中均显著高于男性,COPD(年龄调整后的女性/男性比率=2.39),哮喘(比率=3.95)。然而,研究中的女性生存率高于男性。所有死因、所有呼吸道病因以及COPD导致的男性死亡率均高于女性(COPD患者的风险比率=0.42,0.29 - 0.59,哮喘患者的风险比率=0.11,0.02 - 0.60),但哮喘导致的死亡率并非如此。诊断为COPD的女性哮喘死亡率更高(2.79,1.52 - 5.13),但在诊断为哮喘的个体中无差异(1.02,0.56 - 1.87)。男性COPD病情比女性更严重,这可能解释了男性所有呼吸道病因和COPD的死亡风险更高。女性哮喘死亡风险增加可能是由于死亡证明中“哮喘”一词的编码问题。与普通人群相比,女性死亡率高于男性,可能是因为我们研究人群中吸烟等风险因素在男女之间的相似性高于普通人群中的男女。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验