Shubarov K, Daskalov T R
Vutr Boles. 1976;15(3):15-23.
The level of lactates and pyruvates in arterial blood of 35 patients with myocardial infarction without shock (17-without heart insufficiency and 18-with manifested but in various degrees) is higher as compared with the level of 18 healthy subject and the elevation is better manifested in the patients with cardiac insufficiency. The highest level of lactates and pyruvates is reached in the first 48 hours of the onset of the disease, after which they decrease progressively and in patients without cardiac insufficiency is normalized by the 5-6th day and in those with insufficiency-remains elevated. Slight to moderate correlation exists between the level of lactates and BE and PaCO2. Lacate and pyruvate level reoresents a more sensitive index for the existence of distrubances in the tissue metabolism as compared with the indices of alkaline-acid equilibtrium.
35例无休克的心肌梗死患者（17例无心脏功能不全，18例有不同程度的心脏功能不全表现）动脉血中乳酸和丙酮酸水平高于18例健康受试者，且在心脏功能不全患者中升高更为明显。乳酸和丙酮酸的最高水平在发病后的头48小时达到，此后逐渐下降，无心脏功能不全的患者在第5 - 6天恢复正常，而有心脏功能不全的患者则持续升高。乳酸水平与碱剩余（BE）和动脉血二氧化碳分压（PaCO2）之间存在轻度至中度相关性。与酸碱平衡指标相比，乳酸和丙酮酸水平是组织代谢紊乱存在的更敏感指标。
