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[呋喃西林对心肌梗死急性期若干血流动力学指标的影响]

[Effect of furanthril on several hemodynamic indices during the acute stage of myocardial infarction].

作者信息

Daskalov T, Popnikolov S, Panikian G

出版信息

Vutr Boles. 1976;15(4):17-23.

PMID:1007234
Abstract

Pulmonary arterial pressure, heart rate and peripheral arterial pressure were followed up by the 15th, 45th and 105th minute post intravenous introduction of 40 mg furanthril in patients with myocardial infarction in acute stage (in 42 cases of 12 patients with left cardiac insufficiency and in 14 cases--of 8 patients without cardiac insufficiency). Furanthril induced clearly manifested pressure decrease in the pulmonary artery in patients with left cardiac insufficiency, developing between the 15th and 45th minute and continuing till the end of the second hour and a negligible elevation of peripheral arterial pressure by the 15th minute, followed by a slight decrease of the latter under the initial value by the 45th and 105th minute. Similar tendency, but less manifested, exists and in patients without cardiac insufficiency. Heart rate is kept unchanged. Furanthril does not induce undesirable hypotonic states when applied in those doses in patients who, as a rule, arenot hyptonics.

摘要

在急性期心肌梗死患者(12例左心功能不全患者中的42例以及8例无心功能不全患者中的14例)静脉注射40毫克呋喃西林后的第15、45和105分钟,对肺动脉压、心率和外周动脉压进行了随访。呋喃西林使左心功能不全患者的肺动脉压明显下降,在第15至45分钟之间出现,并持续到第二小时末;外周动脉压在第15分钟时略有升高,随后在第45和105分钟时略低于初始值。在无心功能不全的患者中也存在类似趋势,但表现较弱。心率保持不变。在通常不是低血压患者中以这些剂量应用呋喃西林时,不会引起不良的低血压状态。

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