Isaac S
Saint Barnabas Medical Center, Livingston, New Jersey 07039, USA.
Int J Dermatol. 1998 Aug;37(8):599. doi: 10.1046/j.1365-4362.1998.00508.x.
A 48-year-old alcoholic Filipino man presented to the outpatient department with a 2-year history of an eruption in a photosensitive distribution and episodes of mild diarrhea. He was otherwise in good health. Dermatologic examination revealed a browny-red coloration, with a sharply demarcated erythematous border, affecting both hands and lower forearms, where it was striking in its symmetry (Fig. 1). Around the neck, it was typical of a casal's necklace. The fronts and backs of the legs and the dorsa of the feet were also erythematous. The patient showed no evidence of mental confusion. A clinical diagnosis of pellagra was made based on the morphology, and treatment with nicotinamide 500 mg daily was instituted. The eruption quickly improved and resolved in 2 weeks (Fig. 2).
一名48岁的菲律宾酗酒男子到门诊就诊，有2年光敏性皮疹病史及轻度腹泻发作史。他其他方面健康状况良好。皮肤科检查发现双手和前臂下部呈棕红色，有边界清晰的红斑，对称性明显（图1）。颈部周围是典型的卡萨尔项链样表现。腿部前后及足背也有红斑。患者无精神错乱迹象。根据形态学做出糙皮病的临床诊断，并开始每日给予500毫克烟酰胺治疗。皮疹迅速改善，2周内消退（图2）。
