Kurumaji Y
Division of Dermatology, Higashi-Kawaguchi Hospital, Kawaguchi, Japan.
Dermatology. 1998;197(2):183-6. doi: 10.1159/000017996.
A photo Koebner phenomenon following contact dermatitis due to bufexamac is described. A 52-year-old man presented with dermatitis on his buttocks and an erythema-multiforme (EM)-like eruption near the original lesion and on sun-exposed areas. He had been using bufexamac ointment (Anderm(R)) around and inside the anus for a few weeks before he noticed exacerbation. On patch testing, he exhibited severe contact sensitivity to bufexamac. Phototesting performed on his first visit showed that he had an abnormal reaction to UVB. An EM-like eruption similar to the original lesions developed around the irradiated sites. In this case, photosensitivity does not seem to be a drug-induced photoallergy due to systemic or topical use, but rather a photo Koebner phenomenon.
描述了一例因丁苯羟酸引起接触性皮炎后的同形反应性照片。一名52岁男性，臀部出现皮炎，在原皮损附近及暴露于阳光下的部位出现多形红斑（EM）样皮疹。在他注意到病情加重前几周，一直在肛门周围及内部使用丁苯羟酸软膏（Anderm®）。斑贴试验显示，他对丁苯羟酸表现出严重的接触敏感性。首次就诊时进行的光试验表明，他对紫外线B有异常反应。在照射部位周围出现了与原皮损相似的EM样皮疹。在这种情况下，光敏性似乎并非全身或局部用药引起的药物性光过敏，而是一种同形反应性照片现象。
