Roig E, Orús J, Paré C, Azqueta M, Filella X, Perez-Villa F, Heras M, Sanz G
Cardiovascular Institute, Hospital Clinic, University of Barcelona, Spain.
Am J Cardiol. 1998 Sep 1;82(5):688-90, A8. doi: 10.1016/s0002-9149(98)00388-9.
Increased serum interleukin-6 (IL-6) was associated with a higher incidence of New York Heart Association functional classes III to IV and worse left ventricular function during follow-up. Patients with elevated serum IL-6 had poor prognosis. These results reinforce the concept that increased serum IL-6 may also play an important role in disease progression.
血清白细胞介素-6(IL-6)升高与纽约心脏协会心功能分级III至IV级的较高发生率以及随访期间较差的左心室功能相关。血清IL-6升高的患者预后较差。这些结果强化了血清IL-6升高可能在疾病进展中也起重要作用这一概念。