布洛芬诱发慢性丙型肝炎患者肝毒性：病例系列
Ibuprofen-induced hepatotoxicity in patients with chronic hepatitis C: a case series.
作者信息
Riley T R, Smith J P
机构信息
Penn State Geisinger Health System, The Milton S. Hershey Medical Center, The Pennsylvania State University, Department of Medicine, Hershey 17033-0850, USA.
出版信息
Am J Gastroenterol. 1998 Sep;93(9):1563-5. doi: 10.1111/j.1572-0241.1998.00484.x.
Hepatitis C is a common chronic infection. Nonsteroidal anti-inflammatory drugs are commonly ingested both over-the-counter and by prescription. This case report describes three cases where ibuprofen use leads to a marked rise in hepatic transaminases with one case repeating on rechallenge. These cases support the recommendation of acetaminophen over nonsteroidal antiinflammatory drug use in patients with chronic hepatitis C.
丙型肝炎是一种常见的慢性感染。非甾体类抗炎药无论是非处方药还是处方药都常被服用。本病例报告描述了三例布洛芬使用导致肝转氨酶显著升高的病例，其中一例在再次用药时复发。这些病例支持在慢性丙型肝炎患者中推荐使用对乙酰氨基酚而非非甾体类抗炎药。
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