对乙酰氨基酚肝毒性的酒精性肝病患者中谷草转氨酶/谷丙转氨酶比值升高。
Elevated SGOT/SGPT ratio in alcoholic patients with acetaminophen hepatotoxicity.
作者信息
Himmelstein D U, Woolhandler S J, Adler R D
出版信息
Am J Gastroenterol. 1984 Sep;79(9):718-20.
PMID:6475903
Abstract
Two alcoholic patients with acetaminophen hepatotoxicity are described. Both patients had very high SGOT levels and SGOT/SGPT ratios. It is suggested that a high SGOT/SGPT ratio is not specific for alcoholic hepatitis. Extreme elevations of this ratio, especially in association with SGOT levels greater than five times normal, should suggest nonalcoholic causes of hepatocellular necrosis in alcoholic patients.
摘要
本文描述了两名对乙酰氨基酚肝毒性的酒精性肝病患者。两名患者的谷草转氨酶（SGOT）水平和谷草转氨酶/谷丙转氨酶（SGOT/SGPT）比值都非常高。结果表明，高SGOT/SGPT比值并非酒精性肝炎的特异性表现。该比值的极度升高，尤其是当谷草转氨酶水平高于正常五倍以上时，提示酒精性肝病患者肝细胞坏死可能由非酒精性因素所致。
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