MMWR Morb Mortal Wkly Rep. 1998 Aug 28;47(33):685-8.
On July 26, 1998, CDC and Health Canada, in cooperation with local public health authorities, began investigating reports of febrile respiratory illnesses and associated pneumonia among summer land and sea travelers to Alaska and the Yukon Territory (1). Epidemiologic and laboratory evidence has implicated influenza A virus as the etiologic agent of the outbreak. From June 11 through August 22, completed viral cultures of 101 (48%) of 209 nasopharyngeal specimens have yielded 26 influenza A isolates, four other respiratory viruses, and 71 negative results; results are pending for 108 additional specimens. Of the 26 influenza A isolates, five have been characterized at CDC; all have been identified as influenza A/Sydney/5/97 (H3N2)-like viruses, a strain included in the 1998-99 influenza vaccine. This report presents updated information about the outbreak and includes recommendations for influenza A prevention and control in this setting.
1998年7月26日，美国疾病控制与预防中心（CDC）和加拿大卫生部与当地公共卫生当局合作，开始对前往阿拉斯加和育空地区的夏季陆地及海上旅行者中出现的发热性呼吸道疾病及相关肺炎报告展开调查（1）。流行病学和实验室证据表明，甲型流感病毒是此次疫情的病原体。从6月11日至8月22日，对209份鼻咽标本中的101份（48%）进行的病毒培养已得到26株甲型流感病毒分离株、4种其他呼吸道病毒以及71份阴性结果；另有108份标本的结果待定。在这26株甲型流感病毒分离株中，有5株已在美国疾病控制与预防中心进行了鉴定；所有分离株均被鉴定为甲型/悉尼/5/97（H3N2）类似病毒，这是1998 - 1999年流感疫苗中包含的一种毒株。本报告提供了有关此次疫情的最新信息，并包括在这种情况下预防和控制甲型流感的建议。
